Brain Redox Imaging Using Blood—Brain Barrier-Permeable Nitroxide MRI Contrast Agent
نویسندگان
چکیده
منابع مشابه
Redox-mapping MRI in rodent brain with nitroxide contrast agents
INTRODUCTION Overproduction of reactive oxygen species (ROS) and decreased antioxidant defense system may contribute to numerous brain disorders such as stroke, epilepsy, Parkinson’s disease, and Alzheimer’s disease. Non-invasive evaluation and visualization of oxidative stress is important to elucidate the role of ROS in brain diseases. In order to visualize the effect of ROS in vivo, nitroxid...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 2008
ISSN: 0271-678X,1559-7016
DOI: 10.1038/jcbfm.2008.5